Erice: INTERNATIONAL SCHOOL OF NUCLEAR PHYSICS, 46th COURSE

The HEFTY collaboration has been created to address, in a comprehensive way, the production, transport and hadronization of heavy-flavor particles in heavy-ion collisions, by bringing together state-of-the-art expertise on the various components needed to achieve that. In this talk we focus on recent determinations of nonperturbative transport coefficients in the strongly coupled QGP, for both open and hidden HF particles, by utilizing quantum many-body theory constrained by lattice QCD. We also discuss their implementation into transport models for heavy-ion collisions and with first comparisons to experimental data from the LHC.