29. Oktober 2024
GSI Helmholtzzentrum für Schwerionenforschung GmbH
Europe/Berlin Zeitzone

An AI dose engine for fast carbon ion treatment planning

29.10.2024, 09:45
15m
KBW Lecture Hall (GSI Helmholtzzentrum für Schwerionenforschung GmbH)

KBW Lecture Hall

GSI Helmholtzzentrum für Schwerionenforschung GmbH

Planckstraße 1, 64291 Darmstadt, Germany
Biophysics Session

Sprecher

Frau Anastasiia Quarz (GSI Helmholtzzentrum für Schwerionenforschung GmbH(GSI); TU Darmstadt)

Beschreibung

Ion beam therapy is the most advanced form of radiotherapy, requiring fast, precise, and accurate treatment planning. Speed is a critical factor for cancer patients, as timely interventions can significantly impact outcomes. While Monte Carlo simulations offer high-quality dose calculations, they are too slow for routine clinical workflows. In contrast, analytical pencil beam algorithms deliver faster results, but at the cost of some accuracy. We leverage the Dose Transformer Algorithm (DoTA) [DOI:10.1088/1361-6560/ac692e] to predict input data for the biological effects of carbon ion beams, aiming to achieve Monte Carlo-level quality with a speed comparable to the analytical approach.

Hauptautor

Frau Anastasiia Quarz (GSI Helmholtzzentrum für Schwerionenforschung GmbH(GSI); TU Darmstadt)

Co-Autoren

Frau Angelica De Grigorio (Dipartimento di Fisica, Sapienza Università di Roma, Italy) Dr. Gaia Franciosini (Dipartimento di Scienze di Base e Applicate per l’Ingegneria, Sapienza Universita` di Roma, Roma, Italy) Dr. Angelo Schiavi (Dipartimento di Scienze di Base e Applicate per l’Ingegneria, Sapienza Universita` di Roma, Roma, Italy) Dr. Zoltan Perkó (5Delft University of Technology, Department of Radiation Science and Technology, Delft, The Netherlands) Dr. Lennart Volz (GSI Helmholtzzentrum für Schwerionenforschung GmbH(GSI)) Prof. Vincenzo Patera (Dipartimento di Scienze di Base e Applicate per l’Ingegneria, Sapienza Universita` di Roma, Roma, Italy; INFN (Istituto Nazionale di Fisica Nucleare) section of Roma 1, Rome, Italy ) Prof. Marco Durante (GSI Helmholtzzentrum für Schwerionenforschung GmbH(GSI)) Prof. Christian Graeff (GSI Helmholtzzentrum für Schwerionenforschung GmbH(GSI))

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